Masaomi Iyo Selected Research

Major Depressive Disorder (Major Depressive Disorders)

1/2021	Platelet-derived growth factor BB: A potential diagnostic blood biomarker for differentiating bipolar disorder from major depressive disorder.
1/2021	Serum levels of glial cell line-derived neurotrophic factor as a biomarker for mood disorders and lithium response.
1/2016	Increased Serum Levels of Oxytocin in 'Treatment Resistant Depression in Adolescents (TRDIA)' Group.
1/2016	Effect of mirtazapine versus selective serotonin reuptake inhibitors on benzodiazepine use in patients with major depressive disorder: a pragmatic, multicenter, open-label, randomized, active-controlled, 24-week trial.
1/2015	Milnacipran treatment and potential biomarkers in depressed patients following an initial SSRI treatment failure: a prospective, open-label, 24-week study.
1/2012	Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder.
8/2011	Lack of association between translin-associated factor X gene (TSNAX) and methamphetamine dependence in the Japanese population.
6/2005	No association of the brain-derived neurotrophic factor (BDNF) gene polymorphisms with panic disorder.
6/2005	Serum brain-derived neurotrophic factor (BDNF) levels in patients with panic disorder: as a biological predictor of response to group cognitive behavioral therapy.
6/2004	[Major depressive disorders and BDNF (brain-derived neurotrophic factor)].

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Masaomi Iyo Research Topics

Disease

109	Schizophrenia (Dementia Praecox) 10/2023 - 02/2002
74	Psychotic Disorders (Schizoaffective Disorder) 10/2023 - 02/2002
28	Treatment-Resistant Schizophrenia 10/2023 - 09/2012
14	Feeding and Eating Disorders (Eating Disorder) 11/2023 - 08/2003
14	Cognitive Dysfunction 03/2022 - 05/2004
13	Tardive Dyskinesia 12/2021 - 10/2002
13	Major Depressive Disorder (Major Depressive Disorders) 01/2021 - 07/2003
12	Bipolar Disorder (Manic Depressive Psychosis) 12/2023 - 05/2004
12	Alzheimer Disease (Alzheimer's Disease) 02/2019 - 04/2002
11	Mental Disorders (Mental Disorder) 12/2023 - 07/2003
7	Substance-Related Disorders (Drug Abuse) 03/2008 - 10/2004
6	Bulimia Nervosa 02/2017 - 08/2003
6	Anorexia Nervosa 02/2017 - 08/2003
5	Mood Disorders (Mood Disorder) 01/2021 - 01/2004
4	Disease Progression 01/2022 - 06/2009
4	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2021 - 10/2007
4	Weight Gain 03/2020 - 08/2006
4	Dementia (Dementias) 01/2015 - 01/2013
4	Panic Disorder (Panic Attack) 10/2007 - 06/2004
3	Sleepiness 04/2021 - 01/2013
3	Body Weight (Weight, Body) 01/2021 - 08/2006
3	Genetic Predisposition to Disease (Genetic Predisposition) 01/2020 - 08/2010
3	Mania (Manias) 01/2020 - 02/2004
3	Autistic Disorder (Autism) 11/2007 - 12/2006
2	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2022 - 01/2013
2	Type 2 Diabetes Mellitus (MODY) 09/2021 - 01/2013
2	Psychomotor Agitation (Akathisia) 04/2021 - 06/2019
2	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2021 - 06/2013
2	Movement Disorders (Movement Disorder) 01/2017 - 12/2015
2	Treatment-Resistant Depressive Disorder 01/2016 - 01/2005
2	Social Phobia 01/2016 - 01/2013
2	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2014 - 07/2002

Drug/Important Bio-Agent (IBA)

47	Antipsychotic Agents (Antipsychotics)IBA 10/2023 - 02/2002
41	Dopamine (Intropin)FDA LinkGeneric 10/2023 - 10/2004
39	Methamphetamine (Desoxyn)FDA LinkGeneric 08/2015 - 09/2002
19	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2022 - 02/2002
19	Brain-Derived Neurotrophic Factor (BDNF)IBA 02/2017 - 07/2003
14	N-Methylaspartate (NMDA)IBA 01/2022 - 02/2002
14	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2003
11	Serine (L-Serine)FDA Link 06/2015 - 06/2003
10	Aripiprazole (Abilify)FDA Link 10/2023 - 05/2012
9	Clozapine (Clozaril)FDA LinkGeneric 10/2023 - 02/2003
9	Risperidone (Risperdal Consta)FDA LinkGeneric 09/2019 - 06/2010
7	Proteins (Proteins, Gene)FDA Link 12/2015 - 07/2003
6	Glutamic Acid (Glutamate)FDA Link 03/2011 - 02/2002
6	EnzymesIBA 03/2011 - 09/2002
6	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 08/2010 - 04/2002
6	Glycine (Aminoacetic Acid)FDA LinkGeneric 06/2008 - 02/2002
5	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 07/2022 - 06/2013
5	Lurasidone Hydrochloride FDA Link 04/2021 - 06/2019
5	Fluvoxamine (Luvox)FDA LinkGeneric 10/2012 - 03/2007
5	Phencyclidine (Angel Dust)IBA 01/2012 - 02/2002
5	Glutathione (Reduced Glutathione)IBA 01/2009 - 02/2002
4	Oxytocin (Pitocin)FDA LinkGeneric 10/2022 - 08/2015
4	gamma-Aminobutyric Acid (GABA)IBA 03/2022 - 01/2021
4	ProlactinIBA 01/2021 - 08/2014
4	Olanzapine (Zyprexa)FDA Link 10/2020 - 05/2012
4	Donepezil (Aricept)FDA LinkGeneric 02/2019 - 12/2005
4	Haloperidol (Haldol)FDA LinkGeneric 10/2017 - 06/2004
4	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2016 - 10/2007
4	Antidepressive Agents (Antidepressants)IBA 01/2016 - 07/2003
4	Sigma-1 ReceptorIBA 10/2012 - 03/2007
4	Tropisetron (Navoban)IBA 12/2011 - 07/2005
3	brexpiprazoleIBA 12/2023 - 01/2023
3	ifenprodilIBA 01/2022 - 06/2004
3	blonanserinIBA 04/2021 - 12/2016
3	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 01/2021 - 07/2014
3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2020 - 02/2014
3	Dopamine Receptors (Dopamine Receptor)IBA 01/2017 - 06/2009
3	D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA 06/2015 - 06/2005
3	Serotonin (5 Hydroxytryptamine)IBA 03/2011 - 06/2008
3	Glutamine (L-Glutamine)FDA Link 06/2010 - 01/2005
3	AntioxidantsIBA 01/2009 - 02/2002
3	DNA (Deoxyribonucleic Acid)IBA 10/2008 - 09/2002
2	Glucose (Dextrose)FDA LinkGeneric 01/2024 - 01/2013
2	lemborexantIBA 12/2023 - 01/2022
2	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 11/2023 - 06/2010
2	OrexinsIBA 01/2022 - 08/2015
2	Valproic Acid (Depakote)FDA LinkGeneric 08/2021 - 01/2020
2	Homovanillic AcidIBA 01/2021 - 01/2020
2	LithiumIBA 01/2021 - 01/2005
2	AcidsIBA 01/2021 - 03/2006
2	Paliperidone Palmitate FDA Link 01/2020 - 01/2019
2	Messenger RNA (mRNA)IBA 01/2018 - 07/2003
2	BenzodiazepinesIBA 01/2016 - 11/2010
2	beta-Arrestin 1IBA 12/2015 - 01/2015
2	G-protein-coupled receptor kinase 6IBA 12/2015 - 01/2015
2	Milnacipran (Ixel)FDA Link 01/2015 - 01/2005
2	Yi-Gan SanIBA 01/2015 - 01/2015
2	Therapeutic UsesIBA 03/2013 - 02/2003
2	serine racemaseIBA 01/2013 - 06/2005
2	Cholinergic ReceptorsIBA 12/2011 - 02/2007
2	Purinergic P1 Receptors (Adenosine Receptor)IBA 03/2011 - 08/2010

Therapy/Procedure

11	Therapeutics 04/2021 - 06/2005
7	Drug Therapy (Chemotherapy) 07/2016 - 12/2011
6	Injections 07/2022 - 04/2013
4	Kampo Medicine (Kampo) 01/2014 - 02/2011
3	Aftercare (After-Treatment) 03/2013 - 06/2005
2	Transcranial Magnetic Stimulation 01/2021 - 01/2016
2	Secondary Prevention 10/2013 - 09/2012